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For fluorescence staining, we incubated samples for 2 h with Alexa-488 and Alexa-594 conjugated donkey antibodies (1:200) against mouse and rabbit immunoglobulins (Supplementary Figs 6 and 7 are representative images from two sets of immunolabelled cultures of NPCs and neurons)

With molecules as precise as these, even minor impurities can skew results or introduce confounding variables, rendering months of work useless

Biologics [e.g., TNF- inhibitors (etanercept), IL-6R blockers (tocilizumab)]: Effective in 60 - 70% of patients but incur prohibitive costs ($20,000 - 50,000 annually), limiting accessibility (only 10 - 20% treated in low-resource settings) (5, 6)

According to a study from the US Library of Medicine, fewer than 100 people worldwide have been diagnosed with this condition

Bottom line: When taken as part of a thoughtful, bioavailable routine, glutathione is a powerful ally for renal health and overall cellular vitality