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Where the wider product presentation encourages personal administration or promises physiological effects, the MHRA may consider the complete context

The UK regulator recommends that in adults weighing less than 50 kg, clinical judgement should be employed when prescribing oral paracetamol as these patients may be at increased risk of hepatotoxicity but does not specify a dose reduction

New Trends Clin Neuropharmacol 1989;3(2):131-132

Mitochondrial bioenergetics and quality control mechanisms in health and disease

VAT is the deep fat compartment that surrounds abdominal organs, elevates cardiovascular and metabolic risk markers, and tends to be resistant to diet and exercise interventions that reduce subcutaneous fat