Do not use with other immunosuppressive agents
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Methylene blue can precipitate serotonin syndrome when combined with certain drugs such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and monoamine oxidase inhibitors (MAOIs)
In vitro models of hyperosmolarity-induced DED have indicated that treatment with ATX contributes to an increase of GPX4, promotion of iron storage, and restoration of the mitochondrial structure (125)