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SCD patients have aberrant metabolic regulation of fumarate, glutamate, glycine, malate, and other metabolites involved in glycolysis, nucleotide catabolism, and glutathione metabolism 3,4,5,6

Current literature suggests that KD supports the body's ability to combat oxidative stress by producing ketone bodies, which may alleviate the symptoms of many skin conditions linked to oxidative stress (122)

Given their critical roles in ferroptosis suppression, these antioxidant regulators represent promising therapeutic targets for counteracting ROS-mediated cytotoxicity (Mynott et al., 2023)

The molecular weight of 159.21 g/mol puts it in the optimal range for cellular uptake studies