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The 12mg arm (which produced the 24.2% weight reduction at 48 weeks) followed this retatrutide dosing schedule: Week 1-4: 2mg weekly Week 5-8: 4mg weekly Week 9-12: 8mg weekly Week 13+: 12mg weekly

This lack of significant distinctions between groups could be attributed to the relatively small size of the cohorts, which often necessitates a larger sample size for more reliable results

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Research also suggests that AOD9604 may promote cartilage and bone repair, offering regenerative benefits beyond fat reduction