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And yes, GLP-1s have been associated with medullary thyroid cancer in rats but even some of the rats in those early studies that were taking the placebo (inactive medication) as part of the control group developed thyroid cancer

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Semaglutide, on the other hand, is more focused on regulating blood sugar levels and improving overall metabolic health through weight loss, better cholesterol levels, and lower blood pressure

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In a study of psoriasis patients, TE detected liver fibrosis in 36.1% of those treated with methotrexate, compared to 19.6% in methotrexate-nave controls