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3 Pathology of UC UC progression is attributed to the erosion of mucosal barriers integrity, influenced by environmental and genetic factors, as well as abnormal immune responses that modify complex proteins within tight junctions, leading to increased apoptosis [20, 21]

These mechanisms include endothelial cell damage, inflammatory response exacerbation, fibrosis progression, and other pathways that promote disease occurrence and development (Wang and Zhang, 2022e)

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Avoid foods that trigger GI distress while on tirzepatide, particularly greasy, heavy, or extremely high-fat meals that your slowed digestion will struggle to process