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Weight loss with the supplements is very slight, 1 to 4 pounds at best, White says

The two most significant incretin hormones are GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)

Are they effective

It works by targeting two hormone pathways involved in appetite control and blood sugar regulation, which can lead to stronger reductions in hunger, fewer cravings, and improved portion control for many patients

May offer cardiovascular protection, with possible reductions in cases of major adverse cardiovascular events (MACE) such as myocardial infarction and stroke in high-risk populations 23