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Researchers started every participant at the same base dose regardless of their target maintenance level, then increased the dose every four weeks until reaching the assigned tier

By regulating appetite and energy balance, GLP-1 therapies also support healthier circadian rhythms, enabling patients to achieve more restorative sleep

But because those studies followed different groups of people over different periods of time, researchers eventually compared the medications head-to-head in a roughly 16-month clinical trial involving more than 750 adults with obesity

Cargo holds can reach temperatures below freezing during flight, which permanently destroys the peptide structure