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GLP-1 RAs also delay gastric emptying, which contributes to satiety but may exacerbate symptoms in patients with pre-existing gastroparesis ( Additionally, weight loss with GLP-1 RAs is accompanied by reductions in lean mass, with skeletal muscle accounting for approximately 15%40% of total weight loss (Pandey et al., 2024

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Red wine and carbonated alcoholic beverages pose additional risks because their acidity and gas content irritate an already-sensitive digestive system