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Moreover, experiments are often performed under supraphysiological pressures [47,48,49] that are orders of magnitude larger than those sensed by tumor cells in vivo

On the other hand, MT-II is a cyclic and truncated peptide consisting of seven amino acids, retaining only the His-D-Phe-Arg-Trp (positions three to six in MT-II) sequence from the MT-I molecule (positions six to nine) [5]

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