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These drugs, which work by making people stay fuller for longer, have been found to help people lose over 10% of their body weight

Do NOT shake the vial

Along with regulating your blood sugar, these medications work on receptors in the gut and brain to reduce your appetite and slow gastric emptying, helping you feel fuller for longer

Thus, CHAC1s role in inducing ER stress and ferroptosis highlights its potential as a therapeutic target to increase the efficacy of DTX in treating castration-resistant prostate cancer ( In vivo experiments confirmed that knocking down miR-432-5p in CAFs enhanced CHAC1 expression, increased ferroptosis, and improved the efficacy of docetaxel in reducing tumor growth

Overall, this is in line with the mediation analysis performed by the authors, showing that the effects on glycaemic and weight control are largely separated [4]