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doi: 10.1111/j.1600-0714.2004.00238.x 49 TavaresTSMeirellesDPde AguiarMCFCaldeiraPC

KPV , while primarily anti-inflammatory, contributes by reducing local cytokine-driven endothelial stress, further optimizing conditions for new vessel formation (8)

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found that accumulation of iron and ROS, dysfunction of iron metabolism, decreased GPX4 activity, and mitochondrial atrophy after TBI are all typical characteristics of ferroptosis

However, most of the current evidence is limited and inconsistent