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Tumoral lesions such as onychomatricoma, onychocytic matricoma, onicopapilloma, and Bowen's disease can also present with melanin pigment.3 In cases of LM, the differential diagnosis can be challenging and raises concern not only for general practitioners but also for dermatologists, given the possibility of early-stage nail melanoma

It has no approved drug label, no compounding pharmacy availability, and no recognized dietary supplement status under DSHEA

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For example, naltrexone is contraindicated for individuals who are currently taking opioid pain medications or those who have acute hepatitis or liver failure