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Finally, because selection might take place at other X-linked loci, heterozygotes exhibiting extreme phenotypes by analysis of G6PD may arise from selection acting on an allele at another locus (a hitchhiking effect), as has been suggested in a family with G6PD Ilesha

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Followed by recognition, Dectin-1 promotes the assembly of inflammasomes, activating the production of inflammatory cytokines such as pro-IL-1 and pro-IL-18

nevertheless, their distinct N-terminal residuesglycine, alanine, or aspartic acidmay modestly affect stability and biological efficacy

[PubMed] [Google Scholar] Mendoza J., Garrido T., Riveros R., Gonzalez C., Parada J