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In the oxidized state with two nearby cysteines forming a disulfide bond and the third cysteine unmodified, HMGB1 acts as a proinflammatory cytokine (Yang et al., 2021) which can interact with TLR4 (Pauletti et al., 2019)

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Due to the lack of standardisation the manufacturer can print more or less what they want on their batteries

doi: 10.1038/s41392-022-00967-3 148 HouJWeiYZouJJafferyRLiangSZhengCet al

Regular monitoring is critical when integrating L-carnitine into a recovery plan