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A recent network meta-analysis of RCT comparing incretin-based drugs for the management of obesity in non-diabetic subjects supported the superiority of tirzepatide in achieving a greater percentage of BW loss compared to semaglutide 2.4 mg and liraglutide 3.0 mg (5.13%, 95% CI 9.82 to 0.68, tirzepatide 15 mg vs

The honest answer is that no clinically validated human dosing protocol exists

Solid-state chemical stability of proteins and peptides. Journal of Pharmaceutical Sciences

Direct translation from rodent to human dosing is speculative and potentially unreliable

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