Discussion While there is mounting evidence for the mental health effects of GLP-1 agonists, these cases are the first, to our knowledge, to demonstrate a temporal correlation between administration of tirzepatide, a dual GLP-1/GIP agonist, and improvement in mental health symptoms
Patients typically see HbA1c reductions of 1.01.5% (1116 mmol/mol) with Ozempic therapy, which represents clinically significant improvement in diabetes control
PMID: 4351242
When someone is on a GLP-1, appetite often drops significantly, which means it can become harder to get enough protein, fiber, and nutrients without being very intentional, says Dr
Health authorities discourage its use due to insufficient human safety data, and some jurisdictions have restricted it as a prescription-only medicine despite it not being available through legitimate prescriptions