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423 IFN-2b, a member of the type I interferon family, demonstrates multiple antitumor activities including the suppression of proliferation and angiogenesis, and the enhancement of antitumor immune response through increasing the cytotoxicity of NK cells and tumor antigen processing

However, there may be slight risks associated with certain methods, such as skin irritation, redness, or temporary pigment changes

The maximal effect of desmopressin occurs from 2 to 8 hours after administration, and the duration of action varies form 8 to 24 hours

They are compatible with both hydrophilic and hydrophobic payloads, and can be combined with other linkers to achieve dual-triggered drug release