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Natural compounds evaluated in these models have demonstrated promising results across key pathological pathways, including, reduction of oxidative stress, inhibition of AChE, modulation of inflammatory pathways, preservation of blood-brain barrier integrity, enhancement of spatial and memory-related behaviors

This is supported by a study that compared RRMS patients in relapse and in remission

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Typically, animal OP models are acute, accompanied by drastic metabolic and hormonal changes, which differ significantly from the natural progression of age-related OP and PMO

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