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Prostate cancer is the most common hormone-dependent cancer in men, and the fifth leading cause of cancer-related mortality, partly owing to a lack of knowledge about the mechanisms that lead to aggressive castration-resistant forms

For example, 2.5-micron particulate matter is an environmental pollutant that has been demonstrated to induce iron overload and lipid peroxidation, leading to male reproductive dysfunction [83, 110]

This triple actionextracellular matrix + vascularization + cell migrationis being studied in models of skin repair, wound healing, and connective tissue regeneration

Figure 6 Statements Data availability statement The datasets generated for this study are available on request to the corresponding author

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