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Ang WH, Khalaila I, Allardyce CS, Juillerat-Jeanneret L, Dyson PJ

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Four of the GLP-1RAsalbiglutide, dulaglutide, semaglutide, and liraglutideare GLP-1 analogs, modified from the native structure of GLP-1, while exenatide and lixisenatide are based on the peptide exendin (a hormone derived from the saliva of the Gila monster), which has a similar structure to that of GLP-1 and retains GLP-1 activity [4]

KPV, a tripeptide fragment (lysine-proline-valine) derived from the C-terminus of alpha-melanocyte-stimulating hormone (-MSH), has demonstrated anti-inflammatory activity and a role in modulating immune response, particularly in the skin and gut

Alarming evidence One case report describes a 31-year-old patient with Class III obesity, hypertension, hyperlipidemia, PCOS and anxiety, who underwent an esophagogastroduodenoscopy (EGD) in preparation for bariatric surgery while taking semaglutide