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As the core effector molecule of this pathway, GPX4 is a unique selenoprotein and the only member of the GPX family capable of directly catalyzing the reduction of membrane phospholipid hydroperoxides (30)

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Their ability to be surface-modified allows for targeted delivery, while their biocompatibility, biodegradability, and minimal immunogenicity make them ideal carriers for both therapeutic and diagnostic agents [9, 10]

LgA) or after an animal had earned the maximum of 300 infusions, whichever occurred first