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The most commonly used protocol is 2 to 2.5 mg twice a week during a 4 to 6 week loading phase, followed by 2 mg once a week for maintenance

It has been shown to cause depigmentation by interference with lipid peroxidation of melanocyte membranes, increase in intracellular glutathione content, and inhibition of tyrosinase

Treatment with a GLP-1R agonist over four weeks promotes weight loss-moderated changes in frontal-striatal brain structures in individuals with mood disorders

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N.DurazoA.SunD.et al (2009)