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Scand J Clin Lab Invest 45:193198

Moreover, the communication between MAMs and the coordination of Ca 2+ flux from the ER to mitochondria are pivotal for triggering oxidative metabolic stress, a ROS surge, and an ensuing pro-paraptotic Ca 2+ overload in breast cancer cells [153]

While insomnia is not listed among common adverse reactions in FDA prescribing information or major clinical trials, some patients report sleep disturbances during treatment