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The existing evidence base comes from preclinical (animal) studies conducted primarily at Washington State University, where the compound was developed and patented for potential use in Alzheimer's disease

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Samples were inspected and imaged using a full HD microscopic imaging system (Leica Microsystems GmbH, Wetzlar, Germany)

Cancer Risk Elevated levels of insulin-like growth factor-1 (IGF-1), which is the downstream effect of GH activity, have also raised theoretical concerns about an increased risk of cancer: According to Roberts, IGF-1 promotes cellular proliferation and inhibits apoptosis, two mechanisms that may contribute to the development of cancer cells in predisposed individuals (22)

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