Following the approval of daily injected liraglutide by Novo Nordisk in 2014, branded as Saxenda for treating obesity in selected patient populations, the two leading GLP-1s semaglutide, launched as Wegovy for obesity in 2021, and tirzepatide as Zepbound in obesity in 2023, are now set to transform the treatment of obesity
Muhammad A, Neggers SJ, Van Der Lely AJ
While the drug has generally been well tolerated by patients, like any other medication with side effects, it can have some side effects that can interfere with productivity on a daily basis
Finally, there has been a growing interest in cellular signaling mechanisms altered by acute and chronic exposure to LCACs and Ca 2+ overload mediated by the acylcarnitines [reviewed by Rutkowsky et al., 2014
Some patients using Wegovy Injection notice subtle physical differences, including feeling colder than usual during treatment