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Significant between-study heterogeneity ( I 2 = 709 %, P = 0002) was reduced by subgrouping by study location, treatment duration and type of control (Table 2)

[22] The safety of retatrutide in pregnancy, breastfeeding, children and adolescents, and people with severe gastroparesis is unknown

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Martin and Marion Shirran have spent years working in behavioural weight management, with more than 15,000 hours of one-to-one clinical experience

An additional consideration is that the IGF-3/IGF-1 ratio may be an important factor determining the level of GH stimulation [3]