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Despite similarity in clinical features, it is increasingly clear that the multifactorial nature of AD/ADRD means that the underlying disease processes vary widely across individuals, featuring differences at multiple levels, including genetics, transcriptomics, proteomics, lipidomics, epigenetics, metabolomics, and biochemistry, thus revealing perturbations in many biological pathways including but not limited to myelination, innate immunity, mitochondrial, vascular, and synaptic transmission (Allen et al., 2018

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If a patient suffers harm (e.g., from a dosing error or contamination), the physician may be sued for malpractice

PLoS ONE 18(8):e0289832

Thus, the conclusions of those studies must be further validated, and a wider range of studies is necessary to ensure the reliability of the findings