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Gallbladder monitoring is still relevant, especially for patients with rapid weight loss or biliary history, since cholelithiasis remains the only consistently elevated risk

Zhou J, Xia S, Li T, Liu R

The 50mg High-Concentration Variant is specifically designed for laboratories conducting extended longitudinal studies or high-volume cell culture assays where larger stock solutions are required

It lists personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2, severe gastroparesis, and active pancreatitis as contraindications

Corrigendum: safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes and obesity: a systematic review and meta-analysis