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For example, ferroptotic macrophages have the ability to generate HMGB1, a DAMP that triggers the release of pro-inflammatory cytokines, including IL-1 and IL-18, and activates the inflammasome (61)

Bio/Technology 1991, 9, 830834

Skeletal muscle is a tissue that actively produces high levels of ROS and nitric oxide under certain physiological conditions, especially during exercise, which increases the need for antioxidants to neutralize radicals and prevent damage, as well as maintain levels of NO in the bloodstream

Abstract Estrogens and estrogen-like molecules can modify the biology of several cell types

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