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The medicines work by targeting receptors in the brain and body, including the hunger and reward centers, so food tastes less delicious, leading to weight loss

By supporting healthy melanin levels, it can help promote a more even and radiant skin tone

Sleep consistency a fixed wake time, morning outdoor light, and a 60 to 90 minute wind-down before bed supports cellular recovery and the hormonal balance that underpins cognitive health

weight regain is common after stopping either drug Side effects and safety: what to expect from each medication Gastrointestinal side effects are the most common complaint with both drugs

You might choose Wegovy if: (1) Your insurance covers Wegovy but not Zepbound (CVS Caremark removed Zepbound from formularies July 2025 and prefers Wegovy) [5]