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The kidney toxicity mechanism, specifically the breakdown of D-amino acids by renal enzymes, would likely make extended continuous use problematic

However, this is the exception, not the rule

Often, patients with nerve damage resulting from their Pernicious Anaemia being diagnosed late will be suspected of having Multiple Sclerosis which leads to several expensive and often unpleasant tests before the true nature of their nerve damage is revealed

longer 17-amino-acid thymosin beta-4 fragments in the literature are heavier)