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In experiments with neuronal and astrocyte activation, the parameters were evaluated only during the time windows in which stimulation was not delivered

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The overlapping pathways of our high ADA metabolomic dataset with the studies by Li et al., and Zhou et al., are phenylalanine, tyrosine and tryptophan biosynthesis, phenylalanine metabolism, tyrosine metabolism, arginine biosynthesis, butanoate metabolism and arginine and proline metabolism