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The Wegovy shot, for example, is intended for people whose weight reaches a certain benchmark for obesity or who are overweight and have a condition related to excess weight, such as diabetes, high blood pressure or high cholesterol

These variants are pathway-level and do not predict response to any one compound

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Consult your GP if you experience recurrent episodes (four or more yearly), severe symptoms, first-time symptoms, or if over-the-counter treatments fail

However, multiple lentigines are observed in several genetic disorders including LEOPARD syndrome, Carney complex, Peutz-Jeghers syndrome, Cowden disease, Bannayan-Riley-Ruvalcaba syndrome, xeroderma pigmentosa, and neurofibromatosis type 1 (eTable 361.3 )