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Multivariate analyses (PLSDA and VIP scores) further highlighted proline, glucobrassicin, sinigrin, tryptophan, citric acid, and caffeoylquinic derivatives as key discriminators, enriched in both treatments but more substantially in stress + FFA, reflecting enhanced osmoprotection, redox stability, and secondary metabolism

It was renamed GPER in 2007 by the International Union of Basic and Clinical Pharmacology (IUPHAR) [12], as it contains seven transmembrane domains (TM1-TM7) and is classified as a GPCR (Fig

Many insurance plans either do not cover weight loss medications or require lengthy approval processes with strict criteria

Any imbalance as observed in diabetes mellitus and other metabolic disorders underscores the critical importance of this regulatory mechanism in clinical practice

Your doctor will adjust your dose based on blood tests and clinical response