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Treatment includes controlling blood sugar, medications like duloxetine or pregabalin, and sometimes non-medication therapies to manage symptoms and prevent complications such as ulcers and infections

RORB neurons may be subject to selective degeneration with advancing AD 84 , and ITs more generally have been highlighted to express neuroprotective genes underlying cognitive resilience against AD neuropathology 21

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Depending on the patients clinical picture, we also apply PDRN at this stage