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We propose a mechanism by which a vicious cycle of oxidative stress and neuroinflammation enhances neurodegenerative processes
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Glutathione levels are also found to be decreased in central nervous system disorders (such as Alzheimer disease and Parkinson disease), autism, cardiovascular system disorders (atherosclerosis), peripheral vascular disorders, diabetes and its complications, liver disease, acquired immunodeficiency syndrome/human immunodeficiency virus, and chronic obstructive pulmonary diseases
(April 1986)