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4.2 Clinical impact Despite being statistically significant, the observed metabolic changes are relatively minor compared to the typical physiological changes in pregnancy

Uses The Food and Drug Administration (FDA) has approved both Januvia and metformin to treat high blood sugar caused by type 2 diabetes in adults, along with diet and exercise

These medications are highly effective, and were seeing patients lose weight, improve their health, and in some cases come off blood pressure or diabetes medications, he says

It also produced significant weight loss, and it had been assumed that this accounted for the cardiovascular benefit, he said