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The conventional adenoma-carcinoma pathway occurs after a genomic event triggered by adenomatous polyposis coli mutation, followed by P53 loss of function or KRAS activation, whereas the serrated tumour pathway is characterised by a CpG island methylation phenotype

Image: Javier Zayas Photography /Getty Images About the Author Julie Corliss, Executive Editor, Harvard Heart Letter About the Reviewer Christopher P

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However, it involves a comprehensive approach with optimal medication management, increased physical activity, dietary adjustments, and a focus on stress and sleep

Most side effects associated with sulforaphane are mild and reversible