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Description

Nature Cell Biology , 18 (5), 540548

GCN2 protein kinase is required to activate amino acid deprivation responses in mice treated with the anti-cancer agent L-asparaginase

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Propensity-score matching was used to match 3,456 adolescents using a GLP-1 (mean age, 15.4 years

Participants were allocated in a 21:3:3:7 ratio to weekly injections of one of four regimens: fixed-dose cagrilintide 2.4 mg plus semaglutide 2.4 mg, semaglutide alone, cagrilintide alone, or placebo