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Canadian J Gastroenterol Hepatol 2022(1):4344905

Consistent with the role of KG in de novo carnitine synthesis through TMLHE, we observed an increase in H2AX foci following TMLHE knockdown, which was rescued by l-carnitine and acetylcarnitine, but was not markedly rescued by KG, propionylcarnitine or butyrylcarnitine (Fig