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Jayathilake NJ, Phan TT, Kim J, Lee KP, Park JM

Copper(II)-glycyl-L-histidyl-L-lysine MOLECULAR FORMULA C 28 H 46 CuN 12 O 8 MOLECULAR WEIGHT 742.3 g/mol STRUCTURE Linear tripeptide PEPTIDE SEQUENCE Gly-His-Lys CHEMICAL STRUCTURE CAS Number: 300801-03-0 Molecular Formula : C 28 H 46 CuN 12 O 8 Source: PubChem Mechanism of Action GHK-Cu acts primarily by delivering bioavailable copper(II) to tissues and cells and modulating a range of biological pathways associated with repair and regeneration

One method of treatment and prevention is therapy with the BPC-157 peptide

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The 2015 HUVEC study reported increased VEGF-A expression after BPC-157 exposure, whereas the 2017 endothelial-cell study reported increased VEGFR2 mRNA and protein expression without a corresponding increase in VEGF-A