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Gut microorganisms not only directly synthesize various neuroactive substances, but also indirectly influence neurotransmitter biosynthesis and metabolism by regulating the expression and activity of host neurotransmitter-synthesizing enzymes

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Subsequent work ought to standardize outcomes and reporting and use clinically relevant endpoints

doi: 10.1128/aem.53.12.2821-2826.1987 110 TangH.LiX.ZhangF.MengX.LiuB