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Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux

[DOI] [PubMed] [Google Scholar] 157.Ko CH, Takahashi JS

Moreover, glutathione plays an important role in NO metabolism: glutathione reacts with peroxynitrite from S-nitrosothiols (RSNOs), which subsequently release NO over a prolonged time to extend the half-life of NO, thereby preventing the negative effects of NO scavenging by superoxide

Figure 1 (B) The manganese peroxidase (1YYD) monomer from Phanerochaete chrysosporium and its heme iron plus Mn 3+ (Sundaramoorthy et al., 2005)

There is abundant evidence that alterations in key neurotransmitters can both be modified by and contribute to oxidative stress and membrane dysfunction ( Figure 1 ), suggesting a link among oxidative stress, membrane dysfunction, and multi-neurotransmitter pathologies in SZ (Yao and Keshavan, 2011)