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5.4 GIP and GLP-1 effects on lipid and glucose metabolism in adipose tissue and liver Fat and liver are two organs that play key roles in lipid and glucose metabolism, working together in concert and complimentarily to maintain lipid and glucose homeostasis

You may need to hold your current dose, reduce to a previous lower dose, or consider additional supportive medications

Gastrointestinal actions of glucagon-like peptide-1-based therapies: glycaemic control beyond the pancreas

When administered, it binds to GLP-1 receptors on pancreatic beta cells, stimulating insulin secretion in a glucose-dependent mannermeaning insulin is released only when blood glucose levels are elevated

A person can weigh less but still have a higher-than-ideal body-fat percentage if too much lean mass is lost