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Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials

10.3390/biom11121817 14 CetinA.KaynarL.KocyigitI.HaciogluS

Sample size Sample size was determined according to the phase 2 crossover part of the DIVE-1 study

Result: p53 nuclear exclusion, mitochondrial translocation, and apoptosis

It is one of the most-studied compounds in dermatology and matrix-biology research literature, frequently referenced in pre-clinical models of extracellular-matrix remodelling and gene-expression studies