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Results: The lower HbA1c target strategy, compared to the higher HbA1c target strategy, resulted in an average 0.27 points-per-year slower decline in GCP and a 10.4% relative risk (RR) reduction for dementia

Overall safety profile: Pooled trial data showed no meaningful rise in overall adverse events versus placebo [6] [7]

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Their use must be assessed individually, taking into account existing medications, hormonal therapies, and overall health status