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The resulting models and Sigma-A weighted 2mFo-DFc electron density maps were inspected to assess if the ligands were still observable before refining ligand occupancy with Buster (Supplementary Fig

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International Journal of Molecular Sciences , 24 (19), 14796

And the guidelines should have widespread ramifications for policy decisions in countries where the drugs have not yet been approved

Its role in the management of several important conditions like autism, cystic fibrosis, drug induced hepatic injury, HIV, and many others 1821,50 is just becoming apparent, but the main stumbling block for its therapeutic potential is the route of administration