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B12 deficiency can occur for several reasons, such as Dietary restrictions, Age-related factors, and Certain medical conditions

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Month 15, 18, 21 (Option Period): Quarterly technical progress reports detailing technical progress made, tasks accomplished, major risks/mitigations, a technical plan for the remainder of Phase II Option Period (with necessary updates as in the parenthetical remark for Months 9 and 12), planned activities, trip summaries, and any potential issues or problem areas that require the attention of the DARPA PM

But the study had a small sample, no control group, and self-reported symptom outcomes